Cleveland Guardians (44-49, fourth in the AL Central) vs. Chicago White Sox (32-63, fifth in the AL Central) Chicago; Saturday, 3:10 p.m. CDT PITCHING PROBABLES: Guardians: Tanner Bibee (4-9, 4.27 ERA,

Carlos Santana hit a tiebreaking two-run homer in the sixth inning, and the Cleveland Guardians beat the Chicago White Sox 4-2 in the opener of a split doubleheader.

Preview the July 12 matchup between the Cleveland Guardians and Chicago White Sox with odds over/under, game spread, betting lines and more.

I ts Friday, July 11 and after an afternoon tilt, the Guardians (43-48) and the White Sox (31-62) will take the field for Game 2 of this series. Gavin Williams is slated to take the mound for Cleveland against Jonathan Cannon for Chicago.

Rain washed away the scheduled series opener Thursday between the White Sox and Guardians. The teams will play a split doubleheader Friday.

MLB - Cleveland Guardians vs. Chicago White Sox - 07/12/2025 Major League Baseball Cleveland Guardians Chicago White Sox Mike Tauchman

Chicago White Sox pitching has limited Cleveland Guardians catalysts Steven Kwan and Jose Ramirez to 2-for-17 with three strikeouts through the first two games of a four-game weekend set.

Cleveland Guardians first baseman Kyle Manzardo rejoined the team on Thursday after missing three games to be with his family while his mother underwent a heart transplant. Windy Manzardo had surgery in Spokane,